In The Layover (2017), directed by William H. Macy, Alexandra Daddario stars as Kate Jeffries, a high school English teacher facing professional and personal challenges. Alongside her best friend Meg (Kate Upton), Kate embarks on an impromptu vacation to Fort Lauderdale. Their plans are derailed when a hurricane forces a layover in St. Louis, where both women vie for the affection of fellow traveler Ryan (Matt Barr), leading to comedic and chaotic situations.